The potential effect and delivery of piperine on breast cancer

Breast cancer is the most common malignancy in women worldwide. associated with a high mortality rate and health-related economic burden. patients have low 5-year life expectancy when diagnosed at advanced stages. Besides, emergence of chemoresistance breast has led to an intense search for alternative anticancer agents. One potential compounds Piperine. Several studies had found that Piperine effects such as anti-proliferation, induces apoptosis, anti-migration or anti-metastasis, chemo-enhancer chemosensitizer, cytotoxic agents, anti-angiogenesis, immune response modulators, self-renewal inhibitor stem cells. delivery agents PLGA, PEG-PLGA liposomes been studied improve Piperine's shown good results. Therefore, combination nanoparticles agent, especially cancer.